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Vanatol™ LQ

Butalbital alleviates muscle tension to help treat mild to severe pain caused by headaches.

Acetaminophen relieves headache pain by stopping the pain signals to the brain.

Caffeine increases the effects of pain relievers up to 40%.1,2

Vanatol™ LQ is a prescription medication that helps relieve tension headaches caused by muscle contractions.

Vanatol™ LQ is an orange, tropical fruit punch flavored liquid. Standard dosage is one or two tablespoonfuls (15 mL or 30 mL) every 4 hours. Total daily dosage should not exceed 6 tablespoonfuls. Call your doctor if you take more than the recommended dose. Extended and repeated use of this product is not recommended because of the potential for physical dependence.


1. Laska E.M., Sunshine A., Mueller F., Elvers W.B., Siegel C., Rubin A. Caffeine as an analgesic adjuvant. JAMA. 1984;251(13):1711–1718.

2. Derry C.J., Derry S., Moore R.A. Caffeine as an analgesic adjuvant for acute pain in adults. Cochrane Database Syst Rev. 2014 Dec 11


You may experience drowsiness, lightheadedness, dizziness, sedation, shortness of breath, nausea, vomiting, abdominal pain, and intoxicated feeling.  Discontinue use if you experience signs of hypersensitivity such as swelling of the face, mouth, and throat, respiratory distress, hives, rash, itchy skin, or vomiting.  Do not use Vanatol™ LQ if you are allergic to any of its ingredients.

WARNING:  Hepatotoxicity – Acetaminophen has been associated with cases of acute liver failure, at times resulting in liver transplant and death.  Most of the cases of liver injury are associated with the use of acetaminophen at doses that exceed 4000 milligrams per day, and often involve more than one acetaminophen-containing product.  The risk is higher in individuals with underlying liver disease and those who ingest alcohol while taking acetaminophen.

Rarely, acetaminophen may cause serious skin reactions such as acute generalized exanthematous pustulosis (AGEP), Stevens-Johnson Syndrome, and toxic epidermal necrolysis, which can be fatal.  Patients should be informed about the signs of serious skin reactions, and should discontinue use of the drug at the first appearance of skin rash or any other sign of hypersensitivity. 

There have been post-marketing reports of hypersensitivity and anaphylaxis associated with use of acetaminophen.  Clinical signs included swelling of the face, mouth, and throat, respiratory distress, urticaria, rash, pruritis, and vomiting.  There were infrequent reports of life-threatening anaphylaxis requiring emergency medical attention.  Instruct patients to discontinue Vanatol™ LQ immediately and seek medical care if they experience these symptoms.  Do not prescribe Vanatol™ LQ for patients with acetaminophen allergy.

Butalbital:  Barbiturates may be habit forming.  Tolerance, psychological dependence, and physical dependence may occur especially following prolonged use of high doses of barbiturates. Extended use of this product is not recommended.

This is not a complete list of possible side effects.  Ask your doctor or pharmacist for more information, or see the full Prescribing Information linked below.

Download Prescribing Information

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit, or call 1-800-FDA-1088.